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- **********************************
- * Ribosomal protein S5 signature *
- **********************************
-
- Ribosomal protein S5 is one of the proteins from the small ribosomal subunit.
- In Escherichia coli, S5 is known to be important in the assembly and function
- of the 30S ribosomal subunit. Mutations in S5 have been shown to increase
- translational error frequencies. It belongs to a family of ribosomal proteins
- which, on the basis of sequence similarities [1,2], groups:
-
- - Eubacterial S5.
- - Archaebacterial S5.
- - Cyanelle S5.
- - Mammalian S4 (LLrep3).
- - Yeast S4 (SUP44).
- - Drosophila and rat S2.
-
- S5 is a protein of 166 to 254 amino-acid residues. The signature pattern for
- this protein is based on a conserved region, rich in glycine residues, and
- located in the N-terminal section of these proteins.
-
- -Consensus pattern: [SAGV]-G-[KRQ]-x(3)-[FY]-x-[AC]-x(2)-[LIVMA]-[LIVM]-[AG]-
- [DN]-x(2)-G-x-[LIVM]-G-x-[SAG]-x(5)-[DEQ]-[LIVM]-x(2)-A-
- [LIVM]
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Text revised.
-
- [ 1] All-Robyn J.A., Brown N., Otaka E., Liebman S.W.
- Mol. Cell. Biol. 10:6544-6553(1990).
- [ 2] Otaka E., Hashimoto T., Mizuta K.
- Protein Seq. Data Anal. 5:285-300(1993).
-